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Statements will reflect funds going toward Hoops Fight ALS

Checks can be made out to:

Hoops Fight ALS

c/o Josh Stoler

304 Deer Crossing Rd.

Elgin, SC 29045


Please Place in Memo: 2022 Hoops Fight ALS

PRIMARY BENEFICIARIES

The fundamental mission at the University of Michigan ALS Center of Excellence is to provide exceptional care and advance education, advocacy, and original scientific discovery for ALS patients and their families. ALS is a motor neuron disease without a cure that affects about 30,000 people in the United States. Certified by the ALS Association for more than two decades, the Center offers treatments that manage symptoms and maximize quality of life and functional independence. The Center is also a world leader in research, investigating how and why people develop ALS and creating novel therapies.

The funds raised by this event will be going to a very promising project. The ALS Center of Excellence has identified a new therapeutic target for ALS based on their research on the immune system: Natural Killer (NK) cells. There is an FDA-approved drug, tofacitinib, that specifically blocks NK cells. Their goal is to repurpose tofacitinib for the treatment of ALS. They have just received the patent approval for use of tofacitinib in ALS. This is a major step forward.

In the immune system, NK cells play a key role in combating cancer and infection, but are also responsible for eliminating damaged or dying cells. They discovered that NK cells are increased in the blood of ALS patients; they also discovered that in ALS these killer cells enter the spinal cord and brain and cause injury and disease. The Center of Excellence believes drugs that target NK cells can alter and improve the course of ALS.

Former Michigan Head Basketball Coach, Steve Fisher is a major supporter and speaker in the fight against ALS for the Greater San Diego Chapter. Coach Fisher's fight is personal and he realizes that buildings awareness and seeking funds to combat this disease is crucial towards finding a cure.

***This organization is not affiliated with the Michigan Athletic Department nor the Michigan Basketball Program. This is coordinated and executed solely by several alumni members of Michigan Basketball***


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